Daniel Thomas may refer to:
- Daniel Holcombe Thomas (1906–2000), United States federal judge
- Daniel Edward Thomas (born 1959), American prelate of the Roman Catholic Church
- Daniel M. Thomas, early California politician and pioneer to Los Angeles
- Daniel Lleufer Thomas (1863–1940), Welsh magistrate, social reformer, and writer
- Daniel Thomas (running back) (born 1987), American football (and Canadian football) running back
- Daniel Thomas (safety) (born 1998), American football safety
- Daniel Thomas (athlete) (born 1937), Tanzanian Olympic sprinter
- Daniel Thomas (Emmerdale), a character in the soap opera Emmerdale
- Dan Thomas (infielder), American baseball player
- Dan Thomas (outfielder), American baseball player
- Dan Thomas (footballer) (born 1991), English football goalkeeper
- Dan Thomas (rugby union) (born 1993), Welsh rugby union player