Daphne was a naiad (water nymph) in Greek mythology.
Daphne may also refer to:
- Daphne (opera), a 1938 opera by Richard Strauss based on the myth and legend of the beautiful nymph Daphne
- Daphne (plant), a genus of shrubs in the plant family Thymelaeaceae, noted for their scented flowers and poisonous berries
- 41 Daphne, an asteroid