De materia medica

De materia medica
Cover of an early printed version, Lyon, 1554
AuthorPedanius Dioscorides
Original titleΠερὶ ὕλης ἰατρικῆς
LanguageGreek
SubjectMedicinal plants, drugs
GenreNon-fiction
Publication date
50–70 (50–70)
Publication placeAncient Rome
Published in English
1655 (first English translation)
Media typeManuscript, Print
Pages5 volumes
TextDe materia medica at Wikisource

De materia medica (Greek: Περὶ ὕλης ἰατρικῆς /Peri hulēs iatrikēs/), On Medical Material, is a comprehensive pharmacopoeia on medicinal plants and the medicines derived from them. Written between 50 and 70 CE by Pedanius Dioscorides, a Greek physician in the Roman army, this five-volume encyclopedia became the foremost reference on herbal medicine for over 1,500 years. Its extensive use across Europe and the Middle East until the Renaissance, when it was gradually replaced by revised herbals, makes it one of the most enduring texts in the history of natural history and pharmacology.

The work describes many drugs known to be effective, including aconite, aloes, colocynth, colchicum, henbane, opium and squill. In total, about 600 plants are covered, along with some animals and mineral substances, and around 1000 medicines made from them.

De materia medica was circulated as illustrated manuscripts, copied by hand, in Greek, Latin, and Arabic throughout the medieval period. From the 16th century onwards, Dioscorides' text was translated into Italian, German, Spanish, French, and into English in 1655. It served as the foundation for herbals in these languages by figures such as Leonhart Fuchs, Valerius Cordus, Lobelius, Rembert Dodoens, Carolus Clusius, John Gerard, and William Turner. Over time, these herbals incorporated increasing numbers of direct observations, gradually supplementing and eventually supplanting the classical text.

Several manuscripts and early printed versions of De materia medica survive, including the illustrated Vienna Dioscurides manuscript written in the original Greek in 6th-century Constantinople; it was used there by the Byzantines as a hospital text for just over a thousand years. Sir Arthur Hill saw a monk on Mount Athos still using a copy of Dioscorides to identify plants in 1934.