De re aedificatoria (On the Art of Building) is a classic architectural treatise written by Leon Battista Alberti between 1443 and 1452.[1] Although largely dependent on Vitruvius's De architectura, it was the first theoretical book on the subject written in the Italian Renaissance, and in 1485 it became the first printed book on architecture. It was followed in 1486 with the first printed edition of Vitruvius.