Death

A 17th century painting of various objects, the most prominent of which is a human skull.
The human skull is used universally as a symbol of death.

Death is the end of life; the irreversible cessation of all biological functions that sustain a living organism.[1] The remains of a former organism normally begin to decompose shortly after death.[2] Death eventually and inevitably occurs in all organisms. Some organisms, such as Turritopsis dohrnii, are biologically immortal; however, they can still die from means other than aging.[3] Death is generally applied to whole organisms; the equivalent for individual components of an organism, such as cells or tissues, is necrosis.[4] Something that is not considered an organism, such as a virus, can be physically destroyed but is not said to die, as a virus is not considered alive in the first place.[5]

As of the early 21st century, 56 million people die per year. The most common reason is aging,[6] followed by cardiovascular disease, which is a disease that affects the heart or blood vessels.[7] As of 2022, an estimated total of almost 110 billion humans have died, or roughly 94% of all humans to have ever lived.[8] A substudy of gerontology known as biogerontology seeks to eliminate death by natural aging in humans, often through the application of natural processes found in certain organisms.[9] However, as humans do not have the means to apply this to themselves, they have to use other ways to reach the maximum lifespan for a human, often through lifestyle changes, such as calorie reduction, dieting, and exercise.[10] The idea of lifespan extension is considered and studied as a way for people to live longer.

Determining when a person has definitively died has proven difficult. Initially, death was defined as occurring when breathing and the heartbeat ceased, a status still known as clinical death.[11] However, the development of cardiopulmonary resuscitation (CPR) meant that such a state was no longer strictly irreversible.[12] Brain death was then considered a more fitting option, but several definitions exist for this. Some people believe that all brain functions must cease. Others believe that even if the brainstem is still alive, the personality and identity are irretrievably lost, so therefore, the person should be considered entirely dead.[13] Brain death is sometimes used as a legal definition of death.[14] For all organisms with a brain, death can instead be focused on this organ.[15][16] The cause of death is usually considered important and an autopsy can be done. There are many causes, from accidents to diseases.

Many cultures and religions have a concept of an afterlife that may hold the idea of judgment of good and bad deeds in one's life. There are also different customs for honoring the body, such as a funeral, cremation, or sky burial.[17] After a death, an obituary may be posted in a newspaper, and the "survived by" kin and friends usually go through the grieving process.

  1. ^ "death". Dictionary.com Unabridged (Online). n.d. Retrieved 27 February 2021.
  2. ^ Hayman J, Marc Oxenham (2016). Human body decomposition. Amsterdam: Elsevier. ISBN 978-0-12-803713-3. OCLC 945734521.
  3. ^ Masamoto Y, Piraino S, Miglietta MP (1 December 2019). "Transcriptome Characterization of Reverse Development in Turritopsis dohrnii (Hydrozoa, Cnidaria)". G3: Genes, Genomes, Genetics. 9 (12): 4127–4138. doi:10.1534/g3.119.400487. ISSN 2160-1836. PMC 6893190. PMID 31619459.
  4. ^ Proskuryakov SY, Konoplyannikov AG, Gabai VL (1 February 2003). "Necrosis: a specific form of programmed cell death?". Experimental Cell Research. 283 (1): 1–16. doi:10.1016/S0014-4827(02)00027-7. PMID 12565815. Archived from the original on 13 March 2023. Retrieved 14 February 2023 – via Elsevier Science Direct.
  5. ^ Louten J (2016). Essential Human Virology. Elsevier Science. p. 6. ISBN 978-0-12-801171-3.
  6. ^ url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10750162/#:~:text=The%20top%20ten%20causes%20of,ADOD%2C%201.0%20million)%3B%20lower
  7. ^ Richtie H, Spooner F, Roser M (February 2018). "Causes of death". Our World in Data. Archived from the original on 20 May 2018. Retrieved 14 February 2023.
  8. ^ Routley N (25 March 2022). "How Many Humans Have Ever Lived?". Visual Capitalist. Archived from the original on 28 March 2022. Retrieved 3 October 2023.
  9. ^ Cite error: The named reference Stambler-2017 was invoked but never defined (see the help page).
  10. ^ Cite error: The named reference Fontana-2010 was invoked but never defined (see the help page).
  11. ^ Cite error: The named reference US President's Commission -1981 was invoked but never defined (see the help page).
  12. ^ Cite error: The named reference US Department of the Army-1999 was invoked but never defined (see the help page).
  13. ^ Cite error: The named reference Zaner-2011 was invoked but never defined (see the help page).
  14. ^ "brain death". Dictionary.com Unabridged (Online). n.d. Retrieved 27 February 2021.
  15. ^ DeGrazia D (2021). "The Definition of Death". In Zalta EN (ed.). The Stanford Encyclopedia of Philosophy (Summer 2021 ed.). Metaphysics Research Lab, Stanford University. Archived from the original on 23 July 2022. Retrieved 23 July 2022.
  16. ^ Parent B, Turi A (1 December 2020). "Death's Troubled Relationship With the Law". AMA Journal of Ethics. 22 (12): 1055–1061. doi:10.1001/amajethics.2020.1055. ISSN 2376-6980. PMID 33419507. S2CID 231300316. Archived from the original on 23 July 2022. Retrieved 23 July 2022.
  17. ^ Cite error: The named reference Newcomb-2019 was invoked but never defined (see the help page).