The Deng Maoqi rebellion (simplified Chinese: 邓茂七之乱; traditional Chinese: 鄧茂七之亂; pinyin: Dèng Màoqī zhīluàn) was a peasant revolt that took place in 1448–1449 in the Ming dynasty during the reign of Emperor Yingzong. It occurred in the interior of Fujian in southeastern China. The tenants revolted, refusing to make payments to landlords beyond the scope of their leases. The local militia units were unable to suppress the uprising, and the army had to be sent in. In May 1449, the main forces of the rebels were defeated, and the scattered remnants were destroyed. However, peace was not restored until 1452.
In addition to the Deng Maoqi rebellion, there was also an uprising of miners illegally extracting silver in the border regions of Fujian, Zhejiang, and Jiangxi from 1447 to 1449. This uprising was led by Ye Zongliu (葉宗留).