Dental follicle

Histologic slide showing a tooth bud.
A: enamel organ
B: dental papilla
C: dental follicle

The dental follicle, also known as dental sac, is made up of mesenchymal cells and fibres surrounding the enamel organ and dental papilla of a developing tooth.[1] It is a vascular fibrous sac[2] containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively. Similar to dental papilla, the dental follicle provides nutrition to the enamel organ and dental papilla and also have an extremely rich blood supply.[2]

  1. ^ Chiego DJ (2018). Essentials of oral histology and embryology : a clinical approach (Fifth ed.). St. Louis, Missouri. ISBN 9780323497251. OCLC 1019837103.{{cite book}}: CS1 maint: location missing publisher (link)
  2. ^ a b Creanor S (2016). Essential clinical oral biology. Chichester, West Sussex. ISBN 9781118939666. OCLC 917888653.{{cite book}}: CS1 maint: location missing publisher (link)