| Deputy Prime Minister of the Syrian Arab Republic | |
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| نائب رئيس الوزراء السوري | |
 Seal of the deputy prime minister of Syria | |
| Style | Mr Deputy Prime Minister (informal) His Excellency (diplomatic) |
| Status | Third highest in executive branch |
| Member of | Council of Ministers |
| Reports to | Prime Minister |
| Residence | Government building, Damascus, Syria |
| Nominator | Prime Minister |
| Appointer | President |
| Term length | No term limits |
| Inaugural holder | Mustafa Nehmeh (kingdom) Lutfi al-Haffar (republic) |
| Formation | 23 August 1948 |
| Website | www.pministry.gov.sy |
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The deputy prime minister of Syria (Arabic: نائب رئيس الوزراء السوري) is the deputy to the prime minister of Syria, who is head of the government of Syria, and a member of the Council of Ministers. The deputy prime minister is the second highest-ranking member of the Council of Ministers. In the semi-presidential system of government, the prime minister is treated as the "first among equals" in the cabinet; the position of deputy prime minister is used to bring political stability and strength within a government or in times of national emergency, when a proper chain of command is necessary. As of 2024, the post is Vacant.