| 1921 season | |||
|---|---|---|---|
| Captain | George Buckston | ||
| County Championship | 12 | ||
| Most runs | Samuel Cadman | ||
| Most wickets | Billy Bestwick | ||
| Most catches | Harry Elliott | ||
| |||
Derbyshire County Cricket Club in 1921 represents the cricket season when the English club Derbyshire had been playing for fifty years. It was their twenty-third season in the County Championship and they won five matches to finish twelfth.