Diclofenamide

Diclofenamide

Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601233
ATC code	S01EC02 (WHO)
Pharmacokinetic data
Protein binding	55%
Identifiers
IUPAC name 4,5-Dichlorobenzene-1,3-disulfonamide
CAS Number	120-97-8 Y
PubChem CID	3038
IUPHAR/BPS	6807
DrugBank	DB01144 N
ChemSpider	2930 Y
UNII	VVJ6673MHY
KEGG	D00518 Y
ChEBI	CHEBI:101085 Y
ChEMBL	ChEMBL17 Y
CompTox Dashboard (EPA)	DTXSID1022922
ECHA InfoCard	100.004.037
Chemical and physical data
Formula	C6H6Cl2N2O4S2
Molar mass	305.14 g·mol−1
3D model (JSmol)	Interactive image
Melting point	228.5 °C (443.3 °F)
SMILES Clc1c(cc(cc1Cl)S(=O)(=O)N)S(=O)(=O)N
InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) Y Key:GJQPMPFPNINLKP-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Diclofenamide (or dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-disulfamoylbenzene class. Dichlorphenamide as a carbonic anhydrase inhibitor is used for the treatment of acute angle closure glaucoma. While Dichlorphenamide does contain two sulfate groups within the structure, it falls under the class of a first generation carbonic anhydrase Inhibitor.