Dideoxynucleotide

Molecular structure of 2',3'-dideoxyadenosine triphosphate (ddATP)

Dideoxynucleotides are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing.[1] They are also known as 2',3' because both the 2' and 3' positions on the ribose lack hydroxyl groups, and are abbreviated as ddNTPs (ddGTP, ddATP, ddTTP and ddCTP).[2]

  1. ^ Cite error: The named reference MeisRaghavachari was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Watson_2014 was invoked but never defined (see the help page).