Dipeptidyl-peptidase III

Dipeptidyl-peptidase III
Identifiers
EC no.3.4.14.4
CAS no.77464-87-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Dipeptidyl-peptidase III (EC 3.4.14.4, dipeptidyl aminopeptidase III, dipeptidyl arylamidase III, enkephalinase B, red cell angiotensinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.

This cytosolic peptidase that is active at neutral pH.

  1. ^ McDonald JK (1998). "Dipeptidyl-peptidase III". In Barrett AJ, Rawlings NA, Woessner JG (eds.). Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. pp. 536–538.
  2. ^ Fukasawa K, Fukasawa KM, Iwamoto H, Hirose J, Harada M (June 1999). "The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme". Biochemistry. 38 (26): 8299–303. doi:10.1021/bi9904959. PMID 10387075.