Dipipanone

Dipipanone
Skeletal formula
Ball-and-stick model
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
Pharmacokinetic data
MetabolismLiver
Elimination half-life3.5 hours[2]
Identifiers
  • 4,4-diphenyl-6-(1-piperidinyl)-heptan-3-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.006.728 Edit this at Wikidata
Chemical and physical data
FormulaC24H31NO
Molar mass349.518 g·mol−1
3D model (JSmol)
  • O=C(CC)C(C1=CC=CC=C1)(CC(C)N2CCCCC2)C3=CC=CC=C3
  • InChI=1S/C24H31NO/c1-3-23(26)24(21-13-7-4-8-14-21,22-15-9-5-10-16-22)19-20(2)25-17-11-6-12-18-25/h4-5,7-10,13-16,20H,3,6,11-12,17-19H2,1-2H3 checkY
  • Key:SVDHSZFEQYXRDC-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Dipipanone, sold under the brand names of Pipadone and Diconal[3] is a strong opioid analgesic drug, used for acute pain by mouth (PO) for adults. It is often used in instances where morphine is indicated but cannot be used due to the patient being allergic to morphine. In analgesic potency 25 mg dipipanone is approximately equivalent to 10 mg morphine. [4]

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ^ Paterson S (April 1992). "Pharmacokinetics of dipipanone after a single oral dose". British Journal of Clinical Pharmacology. 33 (4): 449–450. doi:10.1111/j.1365-2125.1992.tb04066.x. PMC 1381337. PMID 1349495.
  3. ^ GB patent 654975, Peter Ofner, Eric Walton, "Improvements relating to the Synthesis of Diphenyl Ketones", published 1948-02-09, issued 1951-07-04 
  4. ^ Swerdlow M (September 1967). "General analgesics used in pain relief: pharmacology". British Journal of Anaesthesia. 39 (9): 699–712. doi:10.1093/bja/39.9.699. PMID 4860888.