 | This article needs more reliable medical references for verification or relies too heavily on primary sources. (February 2022) |  |
| Clinical data | |
|---|---|
| Trade names | Pulmozyme |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a694002 |
| License data |
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| Pregnancy category |
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| Routes of administration | Inhalation |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| DrugBank | |
| ChemSpider |
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| UNII | |
| KEGG | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.029.685 |
| Chemical and physical data | |
| Formula | C1321H1999N339O396S9 |
| Molar mass | 29254.04 g·mol−1 |
  (what is this?) (verify) | |
Dornase alfa, sold under the brand name Pulmozyme, is used for the treatment of cystic fibrosis.[3] It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA.[3] Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions.[3] It is produced in Chinese hamster ovary cells.[3]
- ^ a b Product guildlink.com.au
- ^ "Pulmozyme Product information". Health Canada. 25 April 2012. Retrieved 9 January 2023.
- ^ a b c d e "Pulmozyme- dornase alfa solution". DailyMed. 21 October 2020. Retrieved 9 January 2023.