Doublecortin

DCX
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ATU, 1MJD, 2BQQ, 2XRP, 5IN7, 5IOI, 5IKC, 5IP4, 5IO9
Identifiers
Aliases	DCX, DBCN, DC, LISX, SCLH, XLIS, doublecortin
External IDs	OMIM: 300121; MGI: 1277171; HomoloGene: 7683; GeneCards: DCX; OMA:DCX - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq23 Start 111,293,779 bp[1] End 111,412,429 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F2 Start 142,638,838 bp[2] End 142,716,307 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence ventricular zone tail of epididymis endothelial cell Brodmann area 23 middle temporal gyrus secondary oocyte primary visual cortex Brodmann area 10 Brodmann area 46 Top expressed in Rostral migratory stream trigeminal ganglion barrel cortex ganglionic eminence medial ganglionic eminence superior cervical ganglion human fetus fossa neural tube olfactory bulb More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding protein kinase binding microtubule binding Cellular component cell projection microtubule associated complex microtubule cytoskeleton cytosol neuron projection cytoplasm axoneme Biological process cell differentiation nervous system development multicellular organism development central nervous system development neuron migration intracellular signal transduction axoneme assembly photoreceptor cell development retina development in camera-type eye Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1641 13193 Ensembl ENSG00000077279 ENSMUSG00000031285 UniProt O43602 O88809 RefSeq (mRNA) NM_000555 NM_001195553 NM_178151 NM_178152 NM_178153 NM_001369370 NM_001369371 NM_001369372 NM_001369373 NM_001369374 NM_001110222 NM_001110223 NM_001110224 NM_010025 RefSeq (protein) NP_000546 NP_001182482 NP_835364 NP_835365 NP_835366 NP_001356299 NP_001356300 NP_001356301 NP_001356302 NP_001356303 NP_001103692 NP_001103693 NP_001103694 NP_034155 Location (UCSC) Chr X: 111.29 – 111.41 Mb Chr X: 142.64 – 142.72 Mb PubMed search [3] [4]
Wikidata
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Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X is a protein that in humans is encoded by the DCX gene.^[5]