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The Downing Site is a major site of the University of Cambridge, located in the centre of the city of Cambridge, England, on Downing Street and Tennis Court Road, adjacent to Downing College. The Downing Site is the larger and newer of two city-centre science sites of the university (the other being the New Museums Site). Largely populated with utilitarian brick buildings dating from the 1930s, the more notable buildings include the Zoology Laboratory (1900–04), Sedgwick Museum of Earth Sciences (1904–11) and Downing Street entrance (1904–11).
To the northwest is the New Museums Site and to the southwest is the Old Addenbrooke's Site, two other important University of Cambridge sites.