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The Ascona B-DNA Consortium (ABC) is a collaborative international research initiative founded in 2001 to investigate the sequence-dependent mechanical properties of DNA using molecular dynamics (MD) simulations. The consortium has contributed significantly to the understanding of DNA structure and dynamics over the past two decades, from the atomic level to larger chromatin structures. The ABC's work includes the development of simulation standards, force fields, and data libraries for DNA, enabling the systematic study of sequence effects across different nucleotide configurations.