Drosophila Genetic Reference Panel

Drosophila Genetic Reference Panel (DGRP) is a suite of Drosophila melanogaster lines derived from an out-crossed population in Raleigh, North Carolina. The founders of these lineages were collected from the Raleigh State Farmer's Market[1] 35°45′51″N 78°39′47″W / 35.764254°N 78.662935°W / 35.764254; -78.662935. The suite consists of 205 fully sequenced lines which have been inbred to near homozygosity. The primary goal of the DGRP is to provide a common set of strain for quantitative genetics research in Drosophila. Each researcher who uses the lines from the DGRP will have access to other researchers' data, which will be stored in a publicly available database. This allows for analyses to be performed across studies without having to worry about complications arising from different labs using genomically different lines of fruit flies.[2][3]

  1. ^ "NCDA&CS - Marketing Division - Raleigh Farmers Market". www.ncagr.gov.
  2. ^ [1] Archived 2011-01-01 at the Wayback Machine[full citation needed]
  3. ^ Huang, W.; Massouras, A.; Inoue, Y.; Peiffer, J.; Ramia, M.; Tarone, A. M.; Turlapati, L.; Zichner, T.; Zhu, D.; Lyman, R. F.; Magwire, M. M.; Blankenburg, K.; Carbone, M. A.; Chang, K.; Ellis, L. L.; Fernandez, S.; Han, Y.; Highnam, G.; Hjelmen, C. E.; Jack, J. R.; Javaid, M.; Jayaseelan, J.; Kalra, D.; Lee, S.; Lewis, L.; Munidasa, M.; Ongeri, F.; Patel, S.; Perales, L.; Perez, A.; Pu, L.; Rollmann, S. M.; Ruth, R.; Saada, N.; Warner, C.; Williams, A.; Wu, Y.-Q.; Yamamoto, A.; Zhang, Y.; Zhu, Y.; Anholt, R. R. H.; Korbel, J. O.; Mittelman, D.; Muzny, D. M.; Gibbs, R. A.; Barbadilla, A.; Johnston, J. S.; Stone, E. A.; Richards, S.; Deplancke, B.; Mackay, T. F. C. (8 April 2014). "Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines". Genome Research. 24 (7): 1193–1208. doi:10.1101/gr.171546.113. PMC 4079974. PMID 24714809.