E2F5

E2F5
Identifiers
Aliases	E2F5, E2F-5, E2F transcription factor 5
External IDs	OMIM: 600967; MGI: 105091; HomoloGene: 1472; GeneCards: E2F5; OMA:E2F5 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	85,217,158 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	14,671,369 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; lymph node; ; islet of Langerhans; ; testicle; ; rectum; ; appendix; ; granulocyte; ; tibial nerve; ; right uterine tube;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; somite; ; epiblast; ; abdominal wall; ; primitive streak; ; medial ganglionic eminence; ; tail of embryo; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; transcription factor binding; protein binding; protein dimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	cytoplasm; nucleolus; nucleus; transcription regulator complex; nucleoplasm; fibrillar center; RNA polymerase II transcription regulator complex;
Biological process	animal organ morphogenesis; regulation of cell cycle; cell projection organization; regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	1875
	13559
	ENSG00000133740
	ENSMUSG00000027552
	Q15329
	Q61502
	NM_001083588; NM_001083589; NM_001951
	NM_007892
	NP_001077057; NP_001077058; NP_001942
	NP_031918
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor E2F5 is a protein that in humans is encoded by the E2F5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133740 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027552 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, Chen A, Weinberg RA (Mar 1995). "E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle". Proceedings of the National Academy of Sciences of the United States of America. 92 (6): 2403–7. Bibcode:1995PNAS...92.2403S. doi:10.1073/pnas.92.6.2403. PMC 42492. PMID 7892279.
^ "Entrez Gene: E2F5 E2F transcription factor 5, p130-binding".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000133740 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027552 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7892279-5] Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, Chen A, Weinberg RA (Mar 1995). "E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle". Proceedings of the National Academy of Sciences of the United States of America. 92 (6): 2403–7. Bibcode:1995PNAS...92.2403S. doi:10.1073/pnas.92.6.2403. PMC 42492. PMID 7892279.

[entrez-6] "Entrez Gene: E2F5 E2F transcription factor 5, p130-binding".

[1]

[2]

[3]

[4]

[5]

[6]