EF-G

Protein-synthesizing GTPase
Identifiers
EC no.3.6.5.3
Alt. namesElongation factor G, EF-G
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
Translation elongation factor EFG/EF2
Identifiers
SymbolTransl_elong_EFG/EF2
InterProIPR004540
SCOP21n0u / SCOPe / SUPFAM
EFG/EF2, domain IV
Identifiers
SymbolEFG_IV
PfamPF03764
Pfam clanCL0329
SMARTSM00889
CDDcd01434
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

EF-G (elongation factor G, historically known as translocase) is a prokaryotic elongation factor involved in mRNA translation. As a GTPase, EF-G catalyzes the movement (translocation) of transfer RNA (tRNA) and messenger RNA (mRNA) through the ribosome.[1]

  1. ^ Shoji, S; Walker, SE; Fredrick, K (2009). "Ribosomal translocation: one step closer to the molecular mechanism". ACS Chem Biol. 4 (2): 93–107. doi:10.1021/cb8002946. PMC 3010847. PMID 19173642.