ELF4

ELF4
Identifiers
Aliases	ELF4, ELFR, MEF, E74 like ETS transcription factor 4, AIFBL2
External IDs	OMIM: 300775; MGI: 1928377; HomoloGene: 31036; GeneCards: ELF4; OMA:ELF4 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	130,110,716 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	47,552,009 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; mononuclear cell; ; monocyte; ; cartilage tissue; ; germinal epithelium; ; mucosa of transverse colon; ; mucosa of ileum; ; jejunal mucosa; ; mucosa of sigmoid colon;
	Top expressed in
	granulocyte; ; ascending aorta; ; aortic valve; ; urethra; ; male urethra; ; tibiofemoral joint; ; thymus; ; genital tubercle; ; lip; ; tail of embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	PML body; nucleus; nucleoplasm; nuclear body;
Biological process	natural killer cell proliferation; positive regulation of transcription, DNA-templated; NK T cell proliferation; cell differentiation; innate immune response; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2000
	56501
	ENSG00000102034
	ENSMUSG00000031103
	Q99607
	Q9Z2U4
	NM_001127197; NM_001421
	NM_019680; NM_001381876
	NP_001120669; NP_001412
	NP_062654; NP_001368805
	Wikidata
View/Edit Human	View/Edit Mouse

ETS-related transcription factor Elf-4 is a protein that in humans is encoded by the ELF4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102034 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031103 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Miyazaki Y, Sun X, Uchida H, Zhang J, Nimer S (October 1996). "MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties". Oncogene. 13 (8): 1721–9. PMID 8895518.
^ "Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102034 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031103 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8895518-5] Miyazaki Y, Sun X, Uchida H, Zhang J, Nimer S (October 1996). "MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties". Oncogene. 13 (8): 1721–9. PMID 8895518.

[entrez-6] "Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)".

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