The EMD GP49 is a 4-axle diesel locomotive built by General Motors Electro-Motive Division. Power was provided by an EMD 645F3B 12-cylinder engine which generated 2,800 horsepower (2.09 MW). The GP49 was marketed as one of four models in the 50 series introduced in 1979. The 50 series includes GP/SD49 and GP/SD50. Both the GP and SD50 were relatively popular with a total of 278 GP50s and 427 SD50s built. The SD49 was advertised but never built and a total of nine GP49s were built.
Alaska Railroad was the sole customer that ordered the GP49. In two orders, the company first bought locomotives 2801–2804 in September 1983; locomotives 2805-2809 were subsequently built in May 1985. Six GP39Xs were built in November 1980 for the Southern Railway and upgraded to GP49s shortly thereafter.