ETV4

ETV4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4CO8, 4UUV
Identifiers
Aliases	ETV4, E1A-F, E1AF, PEA3, PEAS3, ETS variant 4, ETS variant transcription factor 4
External IDs	OMIM: 600711; MGI: 99423; HomoloGene: 1504; GeneCards: ETV4; OMA:ETV4 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	43,579,620 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	101,676,197 bp
RNA expression pattern
	Top expressed in
	gonad; ; pituitary gland; ; testicle; ; anterior pituitary; ; mucosa of pharynx; ; pericardium; ; nipple; ; sural nerve; ; gallbladder; ; skin of limb;
	Top expressed in
	palate; ; soft palate; ; tail of embryo; ; cardiac muscle tissue of left ventricle; ; lip; ; palatoglossus muscle; ; epiblast; ; extensor digitorum longus muscle; ; urethra; ; tongue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleolus; nucleus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2118
	18612
	ENSG00000175832
	ENSMUSG00000017724
	P43268
	P28322
NM_001079675; NM_001261437; NM_001261438; NM_001261439; NM_001986;
	NM_001369366; NM_001369367; NM_001369368
	NM_008815; NM_001316365; NM_001316366
NP_001073143; NP_001248366; NP_001248367; NP_001248368; NP_001977;
	NP_001356295; NP_001356296; NP_001356297
	NP_001303294; NP_001303295; NP_032841
	Wikidata
View/Edit Human	View/Edit Mouse

ETS translocation variant 4 (ETV4), also known as polyoma enhancer activator 3 (PEA3), is a member of the PEA3 subfamily of Ets transcription factors.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175832 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000017724 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Isobe M, Yamagishi F, Yoshida K, Higashino F, Fujinaga K (Jul 1995). "Assignment of the ets-related transcription factor E1A-F gene (ETV4) to human chromosome region 17q21". Genomics. 28 (2): 357–9. doi:10.1006/geno.1995.1158. PMID 8530053.
^ "Entrez Gene: ETV4 Ets variant gene 4 (E1A enhancer binding protein, E1AF)".
^ "ETV4 Gene - GeneCards | ETV4 Protein | ETV4 Antibody". www.genecards.org. Retrieved 2019-10-20.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175832 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000017724 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8530053-5] Isobe M, Yamagishi F, Yoshida K, Higashino F, Fujinaga K (Jul 1995). "Assignment of the ets-related transcription factor E1A-F gene (ETV4) to human chromosome region 17q21". Genomics. 28 (2): 357–9. doi:10.1006/geno.1995.1158. PMID 8530053.

[6] "Entrez Gene: ETV4 Ets variant gene 4 (E1A enhancer binding protein, E1AF)".

[7] "ETV4 Gene - GeneCards | ETV4 Protein | ETV4 Antibody". www.genecards.org. Retrieved 2019-10-20.

[1]

[2]

[3]

[4]

[5]

[6]

[7]