 | This article needs more reliable medical references for verification or relies too heavily on primary sources. (December 2021) |  |
| Early-onset Alzheimer's disease | |
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| Other names |
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| Specialty | Neurology |
Early-onset Alzheimer's disease (EOAD), also called younger-onset Alzheimer's disease (YOAD),[1] is Alzheimer's disease diagnosed before the age of 65.[2] It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations. Little is understood about how it starts.
Nonfamilial early-onset AD can develop in people who are in their 30s or 40s, but this is extremely rare,[3] and mostly people in their 50s or early 60s are affected.
- ^ "Younger/ Early-onset Alzheimer's". Alzheimer's Association. Archived from the original on June 29, 2020. Retrieved July 9, 2020.
- ^ "What Are the Signs of Alzheimer's Disease?". National Institute on Aging. National Institutes of Health. October 18, 2022.
- ^ Harvey RJ, Skelton-Robinson M, Rossor MN (September 2003). "The prevalence and causes of dementia in people under the age of 65 years". Journal of Neurology, Neurosurgery, and Psychiatry. 74 (9): 1206–1209. doi:10.1136/jnnp.74.9.1206. PMC 1738690. PMID 12933919.