Early long-term potentiation

Early long-term potentiation (E-LTP) is the first phase of long-term potentiation (LTP), a well-studied form of synaptic plasticity, and consists of an increase in synaptic strength.[1] LTP could be produced by repetitive stimulation of the presynaptic terminals, and it is believed to play a role in memory function in the hippocampus, amygdala and other cortical brain structures in mammals.[2][3]

Long-term potentiation occurs when synaptic transmission becomes more effective as a result of recent activity. The neuronal changes can be temporary and wear off after some hours (early LTP) or much more stable and long-lasting (late LTP).

  1. ^ Cite error: The named reference :5 was invoked but never defined (see the help page).
  2. ^ Huerta P.T., Tonegawa S., Tsien J.Z. (1996). "The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory". Cell. 87 (7): 1327–1338. doi:10.1016/S0092-8674(00)81827-9. PMID 8980238. S2CID 2730362.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ LeDoux J.E., Rogan M.T., Staubli U.V. (1997). "Fear conditioning induces associative long-term potentiation in the amygdala". Nature. 390 (6660): 604–607. Bibcode:1997Natur.390..604R. doi:10.1038/37601. PMID 9403688. S2CID 4310181.{{cite journal}}: CS1 maint: multiple names: authors list (link)