Ecamsule

Ecamsule
Names
	IUPAC name [(3Z)-3-[[4-[(Z)-[7,7-Dimethyl-2-oxo-1-(sulfomethyl)-3-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid
	Other names Mexoryl SX; Terephthalylidene dicamphor sulfonic acid
Identifiers
CAS Number	92761-26-7 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1201133 ;
ChemSpider	4946116 ;
ECHA InfoCard	100.101.049
PubChem CID	6442003;
UNII	M94R1PM439 ;
CompTox Dashboard (EPA)	DTXSID80869056 ;
	InChI InChI=1S/C28H34O8S2/c1-25(2)21-9-11-27(25,15-37(31,32)33)23(29)19(21)13-17-5-7-18(8-6-17)14-20-22-10-12-28(24(20)30,26(22,3)4)16-38(34,35)36/h5-8,13-14,21-22H,9-12,15-16H2,1-4H3,(H,31,32,33)(H,34,35,36)/b19-13-,20-14- Key: HEAHZSUCFKFERC-AXPXABNXSA-N ; InChI=1/C28H34O8S2/c1-25(2)21-9-11-27(25,15-37(31,32)33)23(29)19(21)13-17-5-7-18(8-6-17)14-20-22-10-12-28(24(20)30,26(22,3)4)16-38(34,35)36/h5-8,13-14,21-22H,9-12,15-16H2,1-4H3,(H,31,32,33)(H,34,35,36)/b19-13-,20-14- Key: HEAHZSUCFKFERC-AXPXABNXBW;
	SMILES O=S(=O)(O)CC45C(=O)\C(=C/c1ccc(cc1)/C=C2\C(=O)C3(CCC2C3(C)C)CS(=O)(=O)O)C(CC4)C5(C)C;
Properties
Chemical formula	C28H34O8S2
Molar mass	562.69 g·mol−1
Melting point	255 °C (491 °F; 528 K) (dec)
log P	1.35
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Ecamsule (USAN, trade name Mexoryl SX, INCI terephthalylidene dicamphor sulfonic acid) is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability.^[2]

Although there are a few different UV absorbers with the trade name Mexoryl, only two of them are widely used where approved. Mexoryl SX (water-soluble) and Mexoryl XL (INCI Drometrizole trisiloxane, oil-soluble). Together they show a synergistic effect in protection.^[3] The patents are held by L'Oréal. Sunscreens containing ecamsule are exclusive to L'Oréal and its brands.

^ ^a ^b "ecamsule". www.chemsrc.com.
^ Deflandre A, Lang G (April 1988). "Photostability assessment of sunscreens. Benzylidene camphor and dibenzoylmethane derivatives". International Journal of Cosmetic Science. 10 (2): 53–62. doi:10.1111/j.1467-2494.1988.tb00002.x. PMID 19456910. S2CID 35351113.
^ Moyal D. (October 2004). "Prevention of ultraviolet-induced skin pigmentation". Photodermatol Photoimmunol Photomed. 20 (5): 243–7. doi:10.1111/j.1600-0781.2004.00111.x. PMID 15379874. S2CID 22120937.

[chemsrc-1] "ecamsule". www.chemsrc.com.

[2] Deflandre A, Lang G (April 1988). "Photostability assessment of sunscreens. Benzylidene camphor and dibenzoylmethane derivatives". International Journal of Cosmetic Science. 10 (2): 53–62. doi:10.1111/j.1467-2494.1988.tb00002.x. PMID 19456910. S2CID 35351113.

[3] Moyal D. (October 2004). "Prevention of ultraviolet-induced skin pigmentation". Photodermatol Photoimmunol Photomed. 20 (5): 243–7. doi:10.1111/j.1600-0781.2004.00111.x. PMID 15379874. S2CID 22120937.

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