Elizabeth Johnson may refer to:
- Elizabeth Johnson Jr. (1671–1747), convicted during the Salem witch trials
- Elizabeth Johnson (died 1752) (1689–1752), wife of writer Samuel Johnson
- Elizabeth Johnson (actress) (1771–1830), English stage actress
- Elizabeth Johnson (pamphleteer) (1721–1800), longitude projector
- Eliza McCardle Johnson (1810–1876), wife of US president Andrew Johnson
- Elizabeth Johnson (advocate) (fl. 1870–1901), advocate of Kansas history
- Elizabeth Johnson (theologian) (born 1941), Christian feminist theologian
- Elizabeth Friench Johnson, American college professor
- E. Elizabeth Johnson, Presbyterian biblical scholar
- Betty Johnson (1929–2022), American traditional pop and cabaret singer
- Betsey Johnson (born 1942), American fashion designer
- Betty Johnson (physicist) (1936–2003), American theoretical physicist
- Betsy Johnson (born 1951), American politician in Oregon
- Liz Johnson (bowler) (born 1974), American professional bowler
- Liz Johnson (swimmer) (born 1985), British Paralympic gold medalist
- Elizabeth Johnson, character from American Horror Story: Hotel