Emoxypine

Emoxypine
Clinical data
Trade names	Mexidol
Other names	Emoxipine, Emoxypin, Epigid, 6-Methyl-2-ethyl-3-hydroxypyridine
Routes of; administration	Oral & IV
ATC code	none;
Legal status
Legal status	US: Unscheduled; not FDA approved; RU: Rx only;
Pharmacokinetic data
Elimination half-life	2-2.6 h
Identifiers
	IUPAC name 2-Ethyl-6-methyl-3-hydroxypyridine;
CAS Number	2364-75-2;
PubChem CID	114681;
ChemSpider	102688 ;
UNII	V247P5H4E1;
CompTox Dashboard (EPA)	DTXSID40178313 ;
ECHA InfoCard	100.205.098
Chemical and physical data
Formula	C8H11NO
Molar mass	137.182 g·mol−1
3D model (JSmol)	Interactive image; Interactive image;
Melting point	170 to 172 °C (338 to 342 °F)
	SMILES CCc1c(ccc(n1)C)O; ; Oc1ccc(nc1CC)C;
	InChI InChI=1S/C8H11NO/c1-3-7-8(10)5-4-6(2)9-7/h4-5,10H,3H2,1-2H3; Key:JPGDYIGSCHWQCC-UHFFFAOYSA-N;
	(verify)

Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), also known as Mexidol or Mexifin, a succinate salt, is chemical compound which is claimed by its manufacturer, the Russian company Pharmasoft Pharmaceuticals, to have antioxidant and actoprotector properties,^[2]^[3] but these purported properties of emoxypine have not been proven.^[4] Its chemical structure resembles that of pyridoxine (a type of vitamin B₆).

^ Gruber W (1953). "Synthesis of 3-Hydroxy-2-alkylpyridines". Canadian Journal of Chemistry. 31 (6): 564–568. doi:10.1139/v53-079.
^ "mexidol.ru, Pharmasoft Website". Archived from the original on 2011-04-10. Retrieved 2011-04-27.
^ Yakovlev IY (2013). "Механізми актопротекторної дії похідних янтарної кислоти" [Mechanisms of actoprotective action of succinic acid's derivatives]. Лікарська справа (in Ukrainian) (3): 78–85. PMID 25016753.
^ Cite error: The named reference pmid17117675 was invoked but never defined (see the help page).

[Gruber-1953-1] Gruber W (1953). "Synthesis of 3-Hydroxy-2-alkylpyridines". Canadian Journal of Chemistry. 31 (6): 564–568. doi:10.1139/v53-079.

[mexidol-2011-2] "mexidol.ru, Pharmasoft Website". Archived from the original on 2011-04-10. Retrieved 2011-04-27.

[pmid25016753-3] Yakovlev IY (2013). "Механізми актопротекторної дії похідних янтарної кислоти" [Mechanisms of actoprotective action of succinic acid's derivatives]. Лікарська справа (in Ukrainian) (3): 78–85. PMID 25016753.

[pmid17117675-4] Cite error: The named reference pmid17117675 was invoked but never defined (see the help page).

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