| Endocardial cushions | |
|---|---|
 | |
| Details | |
| Carnegie stage | 14 |
| Days | 27 |
| Precursor | Lateral plate mesoderm[1] |
| Gives rise to | Septum intermedium |
| Identifiers | |
| Latin | tubera endocardiaca atrioventricularia |
| MeSH | D054089 |
| TE | cushions_by_E5.11.1.6.0.0.4 E5.11.1.6.0.0.4 |
| Anatomical terminology | |
Endocardial cushions, or atrioventricular cushions, refer to a subset of cells in the development of the heart that play a vital role in the proper formation of the heart septa.
They develop on the atrioventricular canal[2] and conotruncal region of the bulbus cordis.[3]
During heart development, the heart starts out as a tube. As heart development continues, this tube undergoes remodeling to eventually form the four-chambered heart. The endocardial cushions are a subset of cells found in the developing heart tube that will give rise to the heart's primitive valves and septa, critical to the proper formation of a four-chambered heart.[4]
- ^ Maschhoff KL, Baldwin HS (2000). "Molecular determinants of neural crest migration". Am. J. Med. Genet. 97 (4): 280–8. doi:10.1002/1096-8628(200024)97:4<280::AID-AJMG1278>3.0.CO;2-N. PMID 11376439.
- ^ "endocardial cushions" at Dorland's Medical Dictionary
- ^ Sadler, T. W. (Thomas W.) (2004). Langman's medical embryology. Langman, Jan. (9th ed.). Philadelphia, Pa.: Lippincott Williams & Wilkins. ISBN 0-7817-4310-9. OCLC 51258190.
- ^ Carlson, Bruce M. (2014-01-01), "Development of the Heart", Reference Module in Biomedical Sciences, Elsevier, doi:10.1016/b978-0-12-801238-3.05460-x, ISBN 978-0-12-801238-3, retrieved 2020-12-05