"Cd105" redirects here. For the isotope of cadmium (Cd-105 or
105Cd), see
Cadmium-105.
Protein-coding gene in the species Homo sapiens
ENG |
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Identifiers |
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Aliases | ENG, Eng, AI528660, AI662476, CD105, Endo, S-endoglin, END, HHT1, ORW1, endoglin |
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External IDs | OMIM: 131195; MGI: 95392; HomoloGene: 92; GeneCards: ENG; OMA:ENG - orthologs |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right lung
- right auricle
- apex of heart
- right lobe of thyroid gland
- left ovary
- right ovary
- right coronary artery
- upper lobe of left lung
- ascending aorta
- Descending thoracic aorta
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| Top expressed in | - lactiferous gland
- ankle joint
- right lung
- choroid plexus of fourth ventricle
- cardiac muscle tissue of left ventricle
- right lung lobe
- external carotid artery
- Ileal epithelium
- internal carotid artery
- right ventricle
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| More reference expression data |
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BioGPS | |
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Wikidata |
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Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1.[5] It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis of cancer cells to other locations in the body.