Epitherians comprise all the placentalmammals except the Xenarthra. They are primarily characterized by having a stirrup-shaped stapes in the middle ear, which allows for passage of a blood vessel. This is in contrast to the column-shaped stapes found in marsupials, monotremes, and xenarthrans. They are also characterized by having a shorter fibula relative to the tibia.
Epitheria like Xenarthra and Afrotheria originated after the K-Pg boundary66 million years ago, with the placental diversification occurring within the first hundred thousand years after the K-Pg event and the first modern placental orders began appearing 2–3 million years later.[1] Epitheres are one of the most successful groups of animals.
The monophyly of Epitheria has been challenged by molecular phylogenetic studies.[2] While preliminary analysis of a set of retroposons shared by both Afrotheria, and Boreoeutheria (presence/absence data) supported the Epitheria clade,[3] more extensive analysis of such transposable element insertions around the time of the divergence of Xenarthra, Afrotheria, and Boreoeutheria strongly support the hypothesis of a near-concomitant origin (trifurcation) of these three superorders of mammals.[4][5]
Another analysis suggests that the root of this clade lies between the Atlantogenata and Boreoeutheria.[6]
^O'Leary, M. A.; Bloch, J. I.; Flynn, J. J.; Gaudin, T. J.; Giallombardo, A.; Giannini, N. P.; Goldberg, S. L.; Kraatz, B. P.; Luo, Z.-X.; Meng, J.; Ni, X.; Novacek, M. J.; Perini, F. A.; Randall, Z. S.; Rougier, G. W.; Sargis, E. J.; Silcox, M. T.; Simmons, N. B.; Spaulding, M.; Velazco, P. M.; Weksler, M.; Wible, J. R.; Cirranello, A. L. (2013). "The Placental Mammal Ancestor and the Post-K-Pg Radiation of Placentals". Science. 339 (6120): 662–667. Bibcode:2013Sci...339..662O. doi:10.1126/science.1229237. hdl:11336/7302. ISSN0036-8075. PMID23393258. S2CID206544776.
^For example: Springer, M. (2004). "Molecules consolidate the placental mammal tree". Trends in Ecology & Evolution. 19 (8): 430–438. doi:10.1016/j.tree.2004.05.006. PMID16701301.