Epoetin alfa

Epoetin alfa
Clinical data
Pronunciation/ɛˈpoʊ.ɪtɪn/
Trade namesEpogen
Biosimilarsepoetin alfa-epbx, Abseamed,[1][2] Binocrit,[3] Epoetin Alfa Hexal,[4] Retacrit[5][6]
AHFS/Drugs.comMonograph
MedlinePlusa692034
License data
Routes of
administration		Intravenous, subcutaneous
ATC code
Legal status
Legal status
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC815H1317N233O241S5
Molar mass18396.19 g·mol−1
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Epoetin alfa, sold under the brand name Epogen among others, is a human erythropoietin produced in cell culture using recombinant DNA technology.[8][9] Epoetin alfa is an erythropoiesis-stimulating agent.[8] It stimulates erythropoiesis (increasing red blood cell levels) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy. Epoetin alfa is developed by Amgen.[8]

It is on the World Health Organization's List of Essential Medicines.[10] It was approved for medical use in the European Union in August 2007,

  1. ^ Cite error: The named reference Abseamed EPAR was invoked but never defined (see the help page).
  2. ^ "Abseamed". Union Register of medicinal products. Retrieved 14 January 2021.
  3. ^ Cite error: The named reference Binocrit EPAR was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Epoetin Alfa Hexal EPAR was invoked but never defined (see the help page).
  5. ^ "Retacrit- epoetin alfa-epbx injection, solution". DailyMed. 29 January 2020.
  6. ^ "Retacrit- epoetin alfa-epbx injection, solution". DailyMed. 26 June 2024. Retrieved 25 July 2024.
  7. ^ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
  8. ^ a b c d "Epogen- epoetin alfa solution". DailyMed. 25 July 2018.
  9. ^ Walsh G, Spada S (2005). "Epogen/Procrit". Directory of approved biopharmaceutical products. Boca Raton: CRC Press. pp. 39–41. ISBN 978-0-415-26368-9.
  10. ^ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.