Estrogen receptor beta

ESR2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, estrogen receptor 2, ODG8
External IDsOMIM: 601663; MGI: 109392; HomoloGene: 1100; GeneCards: ESR2; OMA:ESR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_010157
NM_207707

RefSeq (protein)

NP_034287
NP_997590

Location (UCSC)Chr 14: 64.08 – 64.34 MbChr 12: 76.17 – 76.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear receptor which is activated by the sex hormone estrogen.[5] In humans ERβ is encoded by the ESR2 gene.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140009Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021055Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA (June 1996). "Cloning of a novel receptor expressed in rat prostate and ovary". Proceedings of the National Academy of Sciences of the United States of America. 93 (12): 5925–5930. doi:10.1073/pnas.93.12.5925. PMC 39164. PMID 8650195.
  6. ^ Mosselman S, Polman J, Dijkema R (August 1996). "ER beta: identification and characterization of a novel human estrogen receptor". FEBS Letters. 392 (1): 49–53. Bibcode:1996FEBSL.392...49M. doi:10.1016/0014-5793(96)00782-X. PMID 8769313. S2CID 85795649.