Eugene O'Keefe | |
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| Born | 10 December 1827 |
| Died | 1 October 1913 (aged 85) |
| Occupation(s) | Businessman and philanthropist |
| Known for | O'Keefe Brewery Company of Toronto Limited |
Eugene O'Keefe (10 December 1827 – 1 October 1913), baptized as Owen Keeffe, was an Irish-born Canadian businessman and philanthropist, well-known in the brewing industry for his signature brews. He incorporated the O'Keefe Brewery Company of Toronto Limited in 1891.