The non-profit Evidence-based Toxicology Collaboration (EBTC) comprises a group of scientists and experts with ties to governmental and non-governmental agencies, chemical and pharmaceutical companies, and academia that have banded together to promote the use of what are known as "evidence-based approaches" in toxicology.[1] The discipline of evidence-based toxicology (EBT) is a process for transparently, consistently, and objectively assessing available scientific evidence in order to answer questions in toxicology.[2] EBT has the potential to address concerns in the toxicological community about the limitations of current approaches.[1] These include concerns related to transparency in decision making, synthesis of different types of evidence, and the assessment of bias and credibility.[3][4][5]
The evidence-based methods and approaches now being proposed for toxicology are widely used in medicine, which is the basis for their nomenclature.[6] The need to improve how the performance of toxicological test methods is assessed was the main impetus for translating these tools to toxicology.[7]
^Schreider, J.; Barrow, C.; Birchfield, N.; et al. (2010). "Enhancing the credibility of decisions based on scientific conclusions: transparency is imperative". Toxicol Sci. 116 (1): 5–7. doi:10.1093/toxsci/kfq102. PMID20363830.