FAT4

FAT4
Identifiers
AliasesFAT4, CDHF14, CDHR11, FAT-J, FATJ, NBLA00548, VMLDS2, HKLLS2, FAT atypical cadherin 4
External IDsOMIM: 612411; MGI: 3045256; HomoloGene: 14377; GeneCards: FAT4; OMA:FAT4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001291285
NM_001291303
NM_024582

NM_183221

RefSeq (protein)

NP_001278214
NP_001278232
NP_078858
NP_001278214.1
NP_001278232.1

NP_899044

Location (UCSC)Chr 4: 125.31 – 125.49 MbChr 3: 38.94 – 39.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.[5][6]

FAT4 is associated with the Hippo signaling pathway.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196159Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046743Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FAT tumor suppressor homolog 4 (Drosophila)".
  6. ^ Höng JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y (March 2004). "Identification of new human cadherin genes using a combination of protein motif search and gene finding methods". J. Mol. Biol. 337 (2): 307–17. doi:10.1016/j.jmb.2004.01.026. PMID 15003449.
  7. ^ Qi C, Zhu YT, Hu L, Zhu YJ (February 2009). "Identification of Fat4 as a candidate tumor suppressor gene in breast cancers". Int. J. Cancer. 124 (4): 793–8. doi:10.1002/ijc.23775. PMC 2667156. PMID 19048595.