FGF3

FGF3
Identifiers
Aliases	FGF3, HBGF-3, INT2, fibroblast growth factor 3
External IDs	OMIM: 164950; MGI: 95517; HomoloGene: 3841; GeneCards: FGF3; OMA:FGF3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	69,819,416 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	144,398,173 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; spinal cord; ; C1 segment; ; frontal lobe; ; Cortex of frontal lobe; ; ventricle; ; left ventricle; ; integument; ; dorsolateral prefrontal cortex;
	Top expressed in
	embryo; ; inner nuclear layer; ; tail of embryo; ; outer plexiform layer; ; primitive streak; ; endoderm; ; dental papilla; ; mesoderm; ; inner plexiform layer; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	fibroblast growth factor receptor binding; protein binding; growth factor activity; 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein tyrosine kinase activity;
Cellular component	extracellular region; intracellular anatomical structure;
Biological process	cell differentiation; cell-cell signaling; anatomical structure morphogenesis; MAPK cascade; multicellular organism development; fibroblast growth factor receptor signaling pathway; negative regulation of cardiac muscle tissue development; positive regulation of cell population proliferation; positive regulation of cell division; signal transduction; phosphatidylinositol phosphate biosynthetic process; phosphatidylinositol-3-phosphate biosynthetic process; peptidyl-tyrosine phosphorylation; regulation of signaling receptor activity; positive regulation of protein kinase B signaling;
	Sources:Amigo / QuickGO
Orthologs
	2248
	14174
	ENSG00000186895
	ENSMUSG00000031074
	P11487
	n/a
	NM_005247
	NM_008007
	NP_005238
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186895 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031074 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: FGF3 fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186895 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031074 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: FGF3 fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)".

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