FKBP3

FKBP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1PBK, 2KFV, 2MPH, 5D75
Identifiers
Aliases	FKBP3, FKBP-25, FKBP-3, FKBP25, PPIase, FK506 binding protein 3, FKBP prolyl isomerase 3
External IDs	OMIM: 186947; MGI: 1353460; HomoloGene: 1525; GeneCards: FKBP3; OMA:FKBP3 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	45,135,319 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	65,120,781 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; vastus lateralis muscle; ; Skeletal muscle tissue of rectus abdominis; ; Brodmann area 23; ; body of tongue; ; muscle of thigh; ; gastrocnemius muscle; ; sperm; ; thoracic diaphragm; ; right ventricle;
	Top expressed in
	medial vestibular nucleus; ; mammillary body; ; lateral hypothalamus; ; intercostal muscle; ; ventromedial nucleus; ; tail of embryo; ; deep cerebellar nuclei; ; lateral septal nucleus; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	isomerase activity; FK506 binding; peptidyl-prolyl cis-trans isomerase activity; protein binding; RNA binding; signaling receptor activity;
Cellular component	nucleus; cytoplasm;
Biological process	chaperone-mediated protein folding; protein peptidyl-prolyl isomerization;
	Sources:Amigo / QuickGO
Orthologs
	2287
	30795
	ENSG00000100442
	ENSMUSG00000020949
	Q00688
	Q62446
	NM_002013
	NM_013902
	NP_002004
	NP_038930
	Wikidata
View/Edit Human	View/Edit Mouse

FK506-binding protein 3 also known as FKBP25 is a protein that in humans is encoded by the FKBP3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100442 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020949 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hung DT, Schreiber SL (Jun 1992). "cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein". Biochem. Biophys. Res. Commun. 184 (2): 733–8. doi:10.1016/0006-291X(92)90651-Z. PMID 1374240.
^ Porat R, Poutsiaka DD, Miller LC, Granowitz EV, Dinarello CA (May 1992). "Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells". FASEB J. 6 (7): 2482–6. doi:10.1096/fasebj.6.7.1532945. PMID 1532945. S2CID 29899093.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000100442 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020949 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1374240-5] Hung DT, Schreiber SL (Jun 1992). "cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein". Biochem. Biophys. Res. Commun. 184 (2): 733–8. doi:10.1016/0006-291X(92)90651-Z. PMID 1374240.

[pmid1532945-6] Porat R, Poutsiaka DD, Miller LC, Granowitz EV, Dinarello CA (May 1992). "Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells". FASEB J. 6 (7): 2482–6. doi:10.1096/fasebj.6.7.1532945. PMID 1532945. S2CID 29899093.

[entrez-7] Cite error: The named reference entrez was invoked but never defined (see the help page).

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