FOXD4

FOXD4
Identifiers
Aliases	FOXD4, FKHL9, FOXD4A, FREAC-5, FREAC5, forkhead box D4
External IDs	OMIM: 601092; MGI: 1347467; HomoloGene: 83248; GeneCards: FOXD4; OMA:FOXD4 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	118,417 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	24,878,561 bp
RNA expression pattern
	Top expressed in
	cerebellum; ; cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; granulocyte; ; prefrontal cortex; ; putamen; ; stromal cell of endometrium; ; anterior cingulate cortex; ; caudate nucleus;
	Top expressed in
	granulocyte; ; embryo; ; hypoblast; ; embryonic organizer; ; red nucleus; ; endoderm; ; notochord; ; spermatocyte; ; mesoderm; ; spinal ganglia;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; DNA binding, bending; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	2298
	14237
	ENSG00000170122
	ENSMUSG00000051490
	Q12950
	Q60688
	NM_207305
	NM_008022
	NP_997188
	NP_032048
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein D4 is a protein that in humans is encoded by the FOXD4 gene.^[5]^[6]^[7]^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170122 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051490 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Pierrou S, Hellqvist M, Samuelsson L, Enerback S, Carlsson P (Dec 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". EMBO J. 13 (20): 5002–12. doi:10.1002/j.1460-2075.1994.tb06827.x. PMC 395442. PMID 7957066.
^ Larsson C, Hellqvist M, Pierrou S, White I, Enerback S, Carlsson P (Feb 1997). "Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12)". Genomics. 30 (3): 464–9. doi:10.1006/geno.1995.1266. PMID 8825632.
^ Freyaldenhoven BS, Fried C, Wielckens K (Sep 2002). "FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines". Gene. 294 (1–2): 131–140. doi:10.1016/S0378-1119(02)00702-3. PMID 12234674.
^ "Entrez Gene: FOXD4 forkhead box D4".