FOXE3

FOXE3
Identifiers
Aliases	FOXE3, FKHL12, FREAC8, forkhead box E3, AAT11, ASGD2, CTRCT34
External IDs	OMIM: 601094; MGI: 1353569; GeneCards: FOXE3; OMA:FOXE3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	47,418,052 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	114,783,210 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; mucosa of transverse colon; ; tibial nerve; ; putamen; ; cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; kidney; ; left testis;
	Top expressed in
	lens placode; ; subcapsular lens epithelium; ; neural groove; ; surface ectoderm; ; pharynx; ; spinal ganglia; ; neural layer of retina; ; peripheral nervous system; ; spinal cord; ; medulla oblongata;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription regulator complex; nucleus;
Biological process	positive regulation of lens epithelial cell proliferation; regulation of transcription, DNA-templated; negative regulation of lens fiber cell differentiation; cell development; positive regulation of epithelial cell proliferation; iris morphogenesis; cornea development in camera-type eye; negative regulation of apoptotic process; ciliary body morphogenesis; transcription by RNA polymerase II; transcription, DNA-templated; trabecular meshwork development; camera-type eye development; regulation of transcription by RNA polymerase II; eye development; lens development in camera-type eye; mRNA transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	2301
	30923
	ENSG00000186790
	ENSMUSG00000044518
	Q13461
	Q9QY14
	NM_012186
	NM_015758
	NP_036318
	NP_056573
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein E3 (FOXE3) also known as forkhead-related transcription factor 8 (FREAC-8) is a protein that in humans is encoded by the FOXE3 gene located on the short arm of chromosome 1.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186790 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044518 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: forkhead box E3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186790 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044518 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: forkhead box E3".

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