FOXF2

FOXF2
Identifiers
Aliases	FOXF2, FKHL6, FREAC-2, FREAC2, forkhead box F2
External IDs	OMIM: 603250; MGI: 1347479; HomoloGene: 1115; GeneCards: FOXF2; OMA:FOXF2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	1,395,603 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	31,815,386 bp
RNA expression pattern
	Top expressed in
	periodontal fiber; ; urethra; ; gastric mucosa; ; lower lobe of lung; ; pylorus; ; muscle layer of sigmoid colon; ; gonad; ; right lung; ; mucosa of ileum; ; transverse colon;
	Top expressed in
	molar; ; left lung lobe; ; sclerotome; ; tongue; ; mandibular prominence; ; finger; ; urethra; ; genital tubercle; ; Hindgut; ; migratory enteric neural crest cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA-binding transcription factor activity; DNA binding; transcription factor binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding;
Cellular component	transcription regulator complex; nucleus;
Biological process	transcription, DNA-templated; genitalia development; positive regulation of transcription, DNA-templated; roof of mouth development; regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; epithelial to mesenchymal transition; transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation; extracellular matrix organization; establishment of planar polarity of embryonic epithelium; negative regulation of transcription, DNA-templated; embryonic digestive tract development; embryonic camera-type eye morphogenesis; protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of protein polyubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	2295
	14238
	ENSG00000137273
	ENSMUSG00000038402
	Q12947
	O54743
	NM_001452
	NM_010225
	NP_001443
	NP_034355
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein F2 is a protein that in humans is encoded by the FOXF2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137273 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038402 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: FOXF2 forkhead box F2".
^ Pierrou S, Hellqvist M, Samuelsson L, Enerbäck S, Carlsson P (Oct 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002–12. doi:10.1002/j.1460-2075.1994.tb06827.x. PMC 395442. PMID 7957066.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000137273 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038402 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: FOXF2 forkhead box F2".

[pmid7957066-6] Pierrou S, Hellqvist M, Samuelsson L, Enerbäck S, Carlsson P (Oct 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002–12. doi:10.1002/j.1460-2075.1994.tb06827.x. PMC 395442. PMID 7957066.

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