FOXI1

FOXI1
Identifiers
Aliases	FOXI1, FKH10, FKHL10, FREAC-6, FREAC6, HFH-3, HFH3, forkhead box I1
External IDs	OMIM: 601093; MGI: 1096329; HomoloGene: 8140; GeneCards: FOXI1; OMA:FOXI1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	170,109,734 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	34,158,089 bp
RNA expression pattern
	Top expressed in
	human kidney; ; olfactory zone of nasal mucosa; ; minor salivary glands; ; skin of leg; ; renal medulla; ; skin of abdomen; ; tonsil; ; mucosa of transverse colon; ; mammary gland; ; lactiferous gland;
	Top expressed in
	humerus; ; Meckel's cartilage; ; right kidney; ; connecting tubule; ; sphenoid bone; ; submandibular gland; ; basisphenoid; ; rib; ; human kidney; ; basilar part of occipital bone;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA binding, bending; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleolus; intracellular membrane-bounded organelle;
Biological process	positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; inner ear morphogenesis; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation; embryo development ending in birth or egg hatching; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2299
	14233
	ENSG00000168269
	ENSMUSG00000047861
	Q12951
	Q922I5
	NM_012188; NM_144769
	NM_023907
	NP_036320; NP_658982
	NP_076396
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box I1 is a protein that in humans is encoded by the FOXI1 gene.^[5]

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Two transcript variants encoding different isoforms have been found for this gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168269 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047861 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: Forkhead box I1". Retrieved 2011-12-24.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168269 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047861 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Forkhead box I1". Retrieved 2011-12-24.

[1]

[2]

[3]

[4]

[5]