FUCA2

FUCA2
Identifiers
Aliases	FUCA2, dJ20N2.5, fucosidase, alpha-L- 2, plasma, alpha-L-fucosidase 2
External IDs	OMIM: 136820; MGI: 1914098; HomoloGene: 119; GeneCards: FUCA2; OMA:FUCA2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	143,511,720 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	13,394,779 bp
RNA expression pattern
	Top expressed in
	decidua; ; islet of Langerhans; ; stromal cell of endometrium; ; mucosa of ileum; ; rectum; ; monocyte; ; tendon of biceps brachii; ; left adrenal gland; ; left adrenal cortex; ; right adrenal gland;
	Top expressed in
	interventricular septum; ; epithelium of small intestine; ; right kidney; ; proximal tubule; ; human kidney; ; ileum; ; seminal vesicula; ; transitional epithelium of urinary bladder; ; myocardium of ventricle; ; cardiac muscles;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity; alpha-L-fucosidase activity; hydrolase activity, acting on glycosyl bonds; protein binding;
Cellular component	extracellular exosome; extracellular region; extracellular space; azurophil granule lumen; endoplasmic reticulum lumen; lysosome;
Biological process	fucose metabolic process; metabolism; glycoside catabolic process; neutrophil degranulation; post-translational protein modification; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	2519
	66848
	ENSG00000001036
	ENSMUSG00000019810
	Q9BTY2; Q7Z6V2
	Q99KR8
	NM_032020
	NM_025799; NM_001330198
	NP_114409
	NP_001317127; NP_080075
	Wikidata
View/Edit Human	View/Edit Mouse

Plasma alpha-L-fucosidase (see alpha-L-fucosidase) is an enzyme that in humans is encoded by the FUCA2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000001036 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019810 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Eiberg H, Mohr J, Nielsen LS (Oct 1984). "Linkage of plasma alpha-L-fucosidase (FUCA2) and the plasminogen (PLG) system". Clin Genet. 26 (1): 23–9. doi:10.1111/j.1399-0004.1984.tb00782.x. PMID 6590153. S2CID 85371006.
^ "Entrez Gene: FUCA2 fucosidase, alpha-L- 2, plasma".