Fisher's geometric model

Fisher's geometric model (FGM) is an evolutionary model of the effect sizes and effect on fitness of spontaneous mutations[1] proposed by Ronald Fisher to explain the distribution of effects of mutations that could contribute to adaptative evolution.[2]

  1. ^ Fisher, Ronald (1930). The Genetical Theory of Natural Selection. Oxford, UK: Oxford University Press.
  2. ^ Orr, Allen (2005). "The genetic theory of adaptation: a brief history" (PDF). Nature Reviews Genetics. 6 (2): 119–127. doi:10.1038/nrg1523. PMID 15716908. S2CID 17772950.