| cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | |
|---|---|
| Identifiers | |
| Symbol | CELSR1 |
| NCBI gene | 9620 |
| OMIM | 604523 |
| cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | |
|---|---|
| Identifiers | |
| Symbol | CELSR2 |
| Alt. symbols | EGFL2 |
| NCBI gene | 1952 |
| OMIM | 604265 |
| cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) | |
|---|---|
| Identifiers | |
| Symbol | CELSR3 |
| Alt. symbols | EGFL1 |
| NCBI gene | 1951 |
| OMIM | 604264 |
Flamingo is a member of the adhesion-GPCR family of proteins. Flamingo has sequence homology to cadherins and G protein-coupled receptors (GPCR). Flamingo was originally identified as a Drosophila protein involved in planar cell polarity.[1] Mammals have three flamingo homologs, CELSR1, CELSR2, CELSR3. In mice, all three have distinct expression patterns in organs such as the kidney, skin, and lungs, as well as the brain.[2]