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| Floor plate | |
|---|---|
&sq=Envato&lang=en&file=File:Gray642.png) The floor plate separates the left and right basal plates of the developing neural tube. | |
| Details | |
| Precursor | Notochord |
| System | Nervous system |
| Anatomical terminology | |
The floor plate is a structure integral to the developing nervous system of vertebrate organisms. Located on the ventral midline of the embryonic neural tube, the floor plate is a specialized glial structure that spans the anteroposterior axis from the midbrain to the tail regions. It has been shown that the floor plate is conserved among vertebrates, such as zebrafish and mice, with homologous structures in invertebrates such as the fruit fly Drosophila and the nematode C. elegans. Functionally, the structure serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube.[1][2][3]
- ^ "Wolpert, Lewis. Principles of Development: 3rd Edition. Oxford University Press, 2007."
- ^ "Gilbert, Scott F. Principles of Development: 8th Edition. Sinauer Associates, Inc. 2006."
- ^ "Jessell, Thomas M. Neuronal Specification in the spinal cord: inductive signals and transcriptional codes. Nature Reviews Genetics. Oct, 2000(1)"