Florentine painting or the Florentine school refers to artists in, from, or influenced by the naturalistic style developed in Florence in the 14th century, largely through the efforts of Giotto di Bondone, and in the 15th century the leading school of Western painting. Some of the best known painters of the earlier Florentine School are Fra Angelico, Botticelli, Filippo Lippi, the Ghirlandaio family, Masolino, and Masaccio.
Florence was the birthplace of the High Renaissance, but in the early 16th century the most important artists, including Michelangelo and Raphael were attracted to Rome, where the largest commissions then were. In part this was following the Medici, some of whom became cardinals and even the pope. A similar process affected later Florentine artists. By the Baroque period, the many painters working in Florence were rarely major figures.