Fork head domain

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	1d5v, 1e17, 1jxs, 1kq8, 2a3s, 2c6y, 2d2w, 2hdc, 2hfh

Fork head domain
Fork head domain
	Structure of the winged helix protein Genesis.
Identifiers
Symbol	Fork_head
Pfam	PF00250
InterPro	IPR001766
SMART	SM00339
PROSITE	PDOC00564
SCOP2	2hfh / SCOPe / SUPFAM
CDD	cd00059
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	1d5v, 1e17, 1jxs, 1kq8, 2a3s, 2c6y, 2d2w, 2hdc, 2hfh

The fork head domain is a type of protein domain that is often found in transcription factors and whose purpose is to bind DNA.^[2]

^ Marsden I, Jin C, Liao X (May 1998). "Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins". J. Mol. Biol. 278 (2): 293–9. doi:10.1006/jmbi.1998.1703. PMID 9571051.
^ Kaufmann E, Knöchel W (June 1996). "Five years on the wings of fork head". Mech. Dev. 57 (1): 3–20. doi:10.1016/0925-4773(96)00539-4. PMID 8817449. S2CID 18056224.