Formyl peptide receptor 3

FPR3
Identifiers
Aliases	FPR3, FML2_HUMAN, FMLPY, FPRH1, FPRH2, FPRL2, RMLP-R-I, FMLP-R-II, formyl peptide receptor 3
External IDs	OMIM: 136539; HomoloGene: 130500; GeneCards: FPR3; OMA:FPR3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	51,826,190 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; rectum; ; gonad; ; amniotic fluid; ; right coronary artery; ; synovial joint; ; synovial membrane; ; mucosa of sigmoid colon; ; appendix; ; Achilles tendon;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; complement receptor activity; N-formyl peptide receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	chemotaxis; signal transduction; complement receptor mediated signaling pathway; inflammatory response; phospholipase C-activating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; leukocyte migration; cell chemotaxis; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2359
	n/a
	ENSG00000187474
	n/a
	P25089
	n/a
	NM_002030
	n/a
	NP_002021
	n/a
	Wikidata
View/Edit Human

N-formyl peptide receptor 3 (FPR3) is a receptor protein that in humans is encoded by the FPR3 gene.^[3]^[4]^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000187474 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bao L, Gerard NP, Eddy RL, Shows TB, Gerard C (Jun 1992). "Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19". Genomics. 13 (2): 437–40. doi:10.1016/0888-7543(92)90265-T. PMID 1612600.
^ Durstin M, Gao JL, Tiffany HL, McDermott D, Murphy PM (May 1994). "Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes". Biochemical and Biophysical Research Communications. 201 (1): 174–9. doi:10.1006/bbrc.1994.1685. PMID 8198572.
^ "Entrez Gene: FPRL2 formyl peptide receptor-like 2".