GABBR2

GABBR2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4F11, 4F12, 4MQE, 4MQF, 4MR7, 4MR8, 4MR9, 4MRM, 4MS1, 4MS3, 4MS4, 4PAS
Identifiers
Aliases	GABBR2, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099, gamma-aminobutyric acid type B receptor subunit 2, EIEE59, NDPLHS, DEE59
External IDs	OMIM: 607340; MGI: 2386030; HomoloGene: 55902; GeneCards: GABBR2; OMA:GABBR2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	98,708,935 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	46,991,873 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; lateral nuclear group of thalamus; ; middle temporal gyrus; ; endothelial cell; ; superior frontal gyrus; ; Brodmann area 46; ; Brodmann area 10; ; orbitofrontal cortex; ; parietal lobe; ; postcentral gyrus;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; cerebellum; ; hippocampus proper; ; superior frontal gyrus; ; cerebellar cortex; ; hypothalamus; ; striatum of neuraxis; ; olfactory bulb; ; neural layer of retina;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; G protein-coupled receptor activity; G protein-coupled GABA receptor activity; signal transducer activity; protein heterodimerization activity;
Cellular component	cytoplasm; integral component of membrane; neuron projection; cell junction; G protein-coupled receptor heterodimeric complex; plasma membrane; postsynaptic membrane; synapse; integral component of plasma membrane; membrane; GABA receptor complex;
Biological process	gamma-aminobutyric acid signaling pathway; G protein-coupled receptor signaling pathway; negative regulation of adenylate cyclase activity; signal transduction; chemical synaptic transmission; neuron-glial cell signaling;
	Sources:Amigo / QuickGO
Orthologs
	9568
	242425
	ENSG00000136928
	ENSMUSG00000039809
	O75899
	Q80T41
	NM_005458
	NM_001081141
	NP_005449
	NP_001074610
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid (GABA) B receptor, 2 (GABA_B2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136928 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039809 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136928 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000039809 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2".

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